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Updated: Apr 12, 2026

An In Vitro Protocol for Evaluating MicroRNA Levels, Functions, and Associated Target Genes in Tumor Cells
Published on: May 21, 2019
Critical role of miRNAs in pancreatic cancer
Bingya Liu, Xiaoping Zhang, Ai-Wu Mao1
1Interventional Department, Tongren Hospital affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200050, China, maoaiwu@yeah.net.
Abstract:
Pancreatic cancer (PC) is an aggressive malignancy with a high mortality rate and poor prognosis. Numerous investigations have shown that microRNA (miRNA) plays a vital role in PC. Thousands of miRNAs have been screened in PC and altered miRNAs, including circulating miRNAs, are associated with PC proliferation, apoptosis, metastasis, chemosensitivity, and radiosensitivity. Several studies have shown that miRNAs can act as potential diagnostic and prognostic markers. The present review focuses on recent advances regarding the roles of miRNAs in PC and their practical value.
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