Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

An Introduction to Cell Death10:06

An Introduction to Cell Death

56.9K
Necrosis, apoptosis, and autophagic cell death are all manners in which cells can die, and these mechanisms can be induced by different stimuli, such as cell injury, low nutrient levels, or signaling proteins. Whereas necrosis is considered to be an “accidental” or unexpected form of cell death, evidence exists that apoptosis and autophagy are both programmed and “planned” by cells.In this introductory video, JoVE highlights key discoveries pertaining to cell death,...
56.9K
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss09:44

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

19.8K
This article reports the development of a neuro-rehabilitation approach, "constraint-induced sound therapy (CIST)" for sudden sensorineural hearing loss. The aim of CIST is to prevent maladaptive cortical reorganization by using an enriched acoustic environment. CIST represents a safe, easy, inexpensive, and effective approach to treat sudden sensorineural hearing...
19.8K
Quantitative Aspects of Drug-Receptor Interaction01:30

Quantitative Aspects of Drug-Receptor Interaction

1.7K
The receptor occupancy theory connects a drug's response to the number of occupied receptors. With higher drug concentrations, more receptors are occupied, leading to increased responses. The formation of drug-receptor complexes involves association and dissociation rates, which reach equilibrium when the forward and backward reactions are equal. The equilibrium association constant (Ka) and its inverse, the equilibrium dissociation constant (Kd), indicate drug affinity. Higher Ka and lower...
1.7K
Neuronal Death Assay to Evaluate Cell Death in Ex Vivo Epilepsy Model04:25

Neuronal Death Assay to Evaluate Cell Death in Ex Vivo Epilepsy Model

726
This video demonstrates the technique of assessing neuronal death in rhinal cortex-hippocampus organotypic slices. Neuronal death occurs via evolving epileptic seizures — resembling in vivo epilepsy — and is detected through dual-staining of the dead cells using propidium iodide and...
726
Overview of Cell Death01:30

Overview of Cell Death

9.5K
Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
9.5K
Autophagic Cell Death01:18

Autophagic Cell Death

4.4K
Christian de Duve discovered “autophagy,” a process in which cellular components are engulfed by membrane-bound organelles called autophagosomes. The autophagosomes then fuse with lysosomes to digest the enclosed contents. Autophagy is generally activated in cells to prevent cell death. However, cell death is triggered when the damage is beyond repair.
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and...
4.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Visualization of sinus node arteries by multislice spiral computed tomography coronary angiography].

Vestnik rentgenologii i radiologii·2014
Same author

[Structural features of cardiomyocytes in the atrialized right ventricle in patients with Ebstein anomaly].

Arkhiv patologii·2014
Same author

[Modern approaches to diagnostics and surgical correction of brachiocephalic arteries disorders in patients with ischemic heart disease].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2012
Same author

[Clinical and morphological parallels in mitral valve disorders in infants with atrioventricular defect].

Vestnik Rossiiskoi akademii meditsinskikh nauk·2012
Same author

[First experience with monitoring somatosensory and motor evoked potential during operations on the thoracic and thoracoabdominal portions of the aorta].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery·2012
Same author

[Remote results of open interventions in treatment of abdominal aortic aneurysms].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery·2012

Related Experiment Video

Updated: Jan 19, 2026

Surgical Implant Procedure and Wiring Configuration for Continuous Long-Term EEG/ECG Monitoring in Rabbits
08:36

Surgical Implant Procedure and Wiring Configuration for Continuous Long-Term EEG/ECG Monitoring in Rabbits

Published on: January 24, 2025

977

[Sudden death: surgical aspects].

L A Bokeriia

    Vestnik Akademii Meditsinskikh Nauk SSSR
    |January 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    This study explores managing cardiac patients at risk of sudden death, focusing on conditions like sick sinus syndrome and Wolff-Parkinson-White syndrome. It discusses surgical interventions for high-risk arrhythmias and postoperative tachycardia.

    More Related Videos

    Cell Death: Apoptosis, Autophagy and Necrosis
    10:06

    Cell Death: Apoptosis, Autophagy and Necrosis

    Published on: April 29, 2023

    56.9K
    Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
    09:44

    Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

    Published on: January 25, 2016

    19.8K

    Related Experiment Videos

    Last Updated: Jan 19, 2026

    Surgical Implant Procedure and Wiring Configuration for Continuous Long-Term EEG/ECG Monitoring in Rabbits
    08:36

    Surgical Implant Procedure and Wiring Configuration for Continuous Long-Term EEG/ECG Monitoring in Rabbits

    Published on: January 24, 2025

    977
    Cell Death: Apoptosis, Autophagy and Necrosis
    10:06

    Cell Death: Apoptosis, Autophagy and Necrosis

    Published on: April 29, 2023

    56.9K
    Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
    09:44

    Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

    Published on: January 25, 2016

    19.8K

    Area of Science:

    • Cardiology
    • Cardiac Surgery
    • Electrophysiology

    Context:

    • Sudden cardiac death (SCD) management remains a critical challenge, particularly in elderly populations.
    • Sick sinus syndrome (SSS) and Wolff-Parkinson-White (WPW) syndrome are significant contributors to SCD.
    • Ventricular tachycardia (VT), especially coronarogenic VT, poses an elevated SCD risk.

    Purpose:

    • To review and discuss optimal management strategies for patients susceptible to sudden cardiac death.
    • To highlight surgical approaches for managing arrhythmias associated with SCD risk.
    • To analyze operative outcomes in high-risk cardiac patient cohorts.

    Summary:

    • The article addresses under-explored aspects of cardiac surgery concerning the management of patients at risk of sudden death.
    • Specific conditions discussed include sick sinus syndrome, Wolff-Parkinson-White syndrome with atrial fibrillation, and ventricular tachycardia (coronarogenic and postoperative).
    • Surgical methods and their outcomes for these high-risk patient groups are presented.

    Impact:

    • Improved understanding of SCD risk factors in cardiac surgery patients.
    • Guidance on surgical interventions for specific arrhythmias.
    • Potential for enhanced patient outcomes and reduced mortality in high-risk populations.