Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Transposition and Recombination02:13

Overview of Transposition and Recombination

21.2K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
21.2K
DNA-only Transposons02:57

DNA-only Transposons

18.7K
DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
18.7K
Transposons01:24

Transposons

3.1K
Transposons, or "jumping genes," are small mobile genetic elements (MGEs) that range from 700 to 40,000 base pairs in length. They are found in all organisms and can move within the same chromosome or transfer to different chromosomes. In some cases, transposons can also jump between different host DNA molecules, such as plasmids or viruses, contributing to genetic variability.Barbara McClintock first discovered these mobile genetic elements in the 1940s while studying maize genetics, and she...
3.1K
Epigenetic Regulation01:37

Epigenetic Regulation

4.3K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
4.3K
Epigenetic Regulation01:46

Epigenetic Regulation

34.5K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
34.5K
Epigenetic Regulation01:46

Epigenetic Regulation

26.3K
26.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Male sterility in Drosophila hybrids revealed by a multi-generational transcriptomic analysis of genes and transposable elements in testes.

BMC biology·2026
Same author

Transposable elements contribute to the evolution of host shift-related genes in cactophilic <i>Drosophila</i> species.

Genome research·2026
Same author

Sex-biased Expression of Genes and Transposable Elements in Hybrids from Drosophila mojavensis and Drosophila arizonae.

Genome biology and evolution·2025
Same author

Gene and transposable element expression in response to stress in temperate and tropical populations of Drosophila.

Mobile DNA·2025
Same author

Epigenetic Clock Analysis of Sex Chromosome Aneuploidies.

Aging cell·2025
Same author

Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of <i>Drosophila melanogaster</i>.

Evolution letters·2025
Same journal

Clinical spectrum of COVID-19 patients and decreased serum level of miR-146a as a sign of inflammation.

Biomolecular concepts·2025
Same journal

Bio-based hydrogel patches made of κ-carrageenan enriched with degalactosylated xyloglucan for wound dressing applications.

Biomolecular concepts·2025
Same journal

The impact of exercise on mitochondrial biogenesis in skeletal muscle: A systematic review and meta-analysis of randomized trials.

Biomolecular concepts·2025
Same journal

Quest for space: Tenacity of DNA, Protein, and Lipid macromolecules in intracellular crowded environment.

Biomolecular concepts·2025
Same journal

Anti-arthritic potential of crude sulfated polysaccharide from marine macroalgae <i>Sargassum ilicifolium</i> (Turner) C. Agardh: Regulation of cytokine cascade.

Biomolecular concepts·2025
Same journal

Exploring cardiovascular implications in systemic lupus erythematosus: A holistic analysis of complications, diagnostic criteria, and therapeutic modalities, encompassing pharmacological and adjuvant approaches.

Biomolecular concepts·2024
See all related articles

Related Experiment Video

Updated: Apr 12, 2026

Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity
04:04

Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity

Published on: January 20, 2023

2.9K

Evolvability, epigenetics and transposable elements.

Marie Fablet, Cristina Vieira

    Biomolecular Concepts
    |May 12, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Transposable elements (TEs) influence evolvability by providing mutations. Environmental factors affect TE activity and epigenetic regulation, impacting an organism's capacity to adapt.

    More Related Videos

    Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
    11:36

    Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations

    Published on: April 21, 2023

    3.2K
    Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models
    13:47

    Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

    Published on: March 29, 2019

    10.5K

    Related Experiment Videos

    Last Updated: Apr 12, 2026

    Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity
    04:04

    Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity

    Published on: January 20, 2023

    2.9K
    Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
    11:36

    Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations

    Published on: April 21, 2023

    3.2K
    Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models
    13:47

    Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

    Published on: March 29, 2019

    10.5K

    Area of Science:

    • Evolutionary biology
    • Genetics
    • Epigenetics

    Background:

    • Evolvability is the ability of an organism to evolve and acquire adaptive mutations.
    • Transposable elements (TEs) are key sources of genomic mutations.
    • TE transposition rates and copy number are sensitive to environmental conditions.

    Purpose of the Study:

    • To review the relationship between transposable elements and organismal evolvability.
    • To explore the role of epigenetics in mediating TE regulation and its impact on evolution.

    Main Methods:

    • Literature review
    • Synthesis of existing research on TEs, epigenetics, and evolution

    Main Results:

    • TEs contribute significantly to the mutation rate, influencing evolvability.
    • Epigenetic mechanisms play a crucial role in controlling TE activity.
    • Environmental sensitivity of TE regulation suggests a dynamic interplay with evolutionary potential.

    Conclusions:

    • Transposable elements are integral to understanding evolvability.
    • Epigenetic regulation of TEs is a critical factor in adaptive evolution.
    • Revisiting evolvability through the lens of TEs and epigenetics offers new insights.