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Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL

Benshang Li1, Hui Li2, Yun Bai3

  • 11] Key Laboratory of Pediatric Hematology and Oncology Ministry of Health, Department of Hematology and Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [2] Shanghai Ministry of Science and Technology Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China. [3] Pediatric Translational Medicine Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Nature Medicine
|May 12, 2015
PubMed

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