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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Apr 12, 2026

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
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[Aflibercept in clinical practice].

J Bajaček, A Bieliková

    Ceska a Slovenska Oftalmologie : Casopis Ceske Oftalmologicke Spolecnosti a Slovenske Oftalmologicke Spolecnosti
    |May 13, 2015
    PubMed
    Summary
    This summary is machine-generated.

    This study evaluated aflibercept for wet age-related macular degeneration, showing its effectiveness and safety in treating subretinal neovascular membranes over 10 months.

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    Area of Science:

    • Ophthalmology
    • Retinal Diseases
    • Pharmacological Treatments

    Background:

    • Age-related macular degeneration (AMD) is a leading cause of vision loss.
    • Wet AMD involves abnormal blood vessel growth under the retina.
    • Subretinal neovascular membranes are a key feature of wet AMD.

    Observation:

    • This study presents the initial clinical experience with aflibercept.
    • The evaluation covers the first 10 months of treatment.
    • Effectiveness and safety were assessed in patients with wet AMD.

    Findings:

    • Aflibercept demonstrated effectiveness in treating wet AMD.
    • The drug was found to be safe for patients with subretinal neovascular membranes.
    • Initial results support aflibercept's role in managing this condition.

    Implications:

    • These findings suggest aflibercept is a viable treatment option for wet AMD.
    • Further research can explore long-term outcomes and comparisons with other therapies.
    • This contributes to the growing body of evidence for anti-VEGF treatments in retinal diseases.