Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sandifer syndrome reconsidered.

H Mandel1, E Tirosh, M Berant

  • 1Department of Pediatrics, Rambam Medical Center, Haifa, Israel.

Acta Paediatrica Scandinavica
|September 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A giant exoplanet orbiting a very-low-mass star challenges planet formation models.

Science (New York, N.Y.)·2019
Same author

Expanding the MYBPC1 phenotypic spectrum: a novel homozygous mutation causes arthrogryposis multiplex congenita.

Clinical genetics·2015
Same author

Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a consensus conference proposal for a standardized approach.

Bone marrow transplantation·2010
Same author

Television system for the measurement of atmospheric OTF degradation.

Applied optics·2010
Same author

Methods for a prompt and reliable laboratory diagnosis of Pompe disease: report from an international consensus meeting.

Molecular genetics and metabolism·2007
Same author

Genetic basis for correction of very-long-chain acyl-coenzyme A dehydrogenase deficiency by bezafibrate in patient fibroblasts: toward a genotype-based therapy.

American journal of human genetics·2007

Sandifer syndrome can mimic neurological disorders in children. Early recognition of this condition is crucial for accurate diagnosis and appropriate treatment, avoiding unnecessary medical interventions.

Area of Science:

  • Pediatric Neurology
  • Gastroenterology

Background:

  • Sandifer syndrome is a rare condition characterized by intermittent paroxysmal postural abnormalities.
  • It is often associated with gastroesophageal reflux disease (GERD) in infants and children.

Observation:

  • This study describes three pediatric cases of Sandifer syndrome.
  • One patient was initially misdiagnosed with a neurological disease.
  • Two patients had underlying neurological damage that complicated the initial interpretation of their dystonic symptoms.

Findings:

  • Sandifer syndrome can present with bizarre dystonic features that may be mistaken for primary neurological conditions.
  • The association between GERD and these dystonic movements is a key diagnostic clue.

Implications:

Related Experiment Videos

  • Increased awareness of Sandifer syndrome among clinicians is essential to prevent misdiagnosis.
  • Prompt diagnosis can spare children from unnecessary neurological investigations and suffering.
  • Appropriate treatment, often involving GERD management, can resolve the dystonic symptoms.