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Updated: Apr 12, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
[Tend to second-line therapy in lung cancer]
Haruki Kobayashi1, Toshiaki Takahashi
1Division of Thoracic Oncology, Shizuoka Cancer Center.
Abstract:
Second-line chemotherapy has been established for non-small-cell lung cancer(NSCLC)and sensitive relapsed small cell lung cancer(SCLC).Molecular targeted drugs, such as EGFR- and ALK-inhibitors, have improved survival outcome remarkably in patients with NSCLC harboring EGFR mutations or EML4-ALK fusion proteins.In addition, targeted drugs that may overcome T790M-mediated EGFR-TKI resistance have been developed, and the development of future therapeutic strategies is anticipated.On the other hand, molecular targeted drugs against SCLC have not yet been developed.
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