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Updated: Apr 12, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
[Three cases of esophageal carcinoma achieved a pathological complete response after neoadjuvant chemotherapy with
Hidehito Oyanagi1, Hiroshi Ichikawa, Shinichi Kosugi
1Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences.
Abstract:
We report three cases of esophageal carcinoma all of which achieved a pathological complete response after neoadjuvant chemotherapy (NAC) with cisplatin and 5-fluorouracil (CF). All three patients were men with clinical stage II squamous cell carcinoma of the middle thoracic esophagus. We administered 2 courses of CF treatment as NAC and then performed radical esophagectomy. Pathologic examination revealed no viable tumor cells in the resected esophagus. The patients are currently alive with no evidence of disease.

