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Updated: Jul 19, 2026
An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
Published on: July 28, 2012
Radiation-induced Chondrosarcoma of the Bladder. Case Report and Review of Literature
Norbert Sule1, B O Xu2, Dima El Zein3
1Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY, U.S.A. Norbert.Sule@RoswellPark.org.
Background:
Chondrosarcoma of the bladder is an extremely rare disease. Only five previously described cases are known in the medical literature.
Patients And Methods:
We present a chondrosarcoma developed 19 years after radiation treatment in a 73-year-old patient. A literature search of articles published from 1984 to 2014 was performed.
Results:
This is the first reported case of post-radiation bladder chondrosarcoma. We compared the clinicopathological features of the previously reported cases and reviewed the medical literature of the bladder sarcomas and post-radiation sarcomas.
Conclusion:
The primary treatment for bladder mesenchymal neoplasms is surgical, preferably radical cystectomy with or without chemotherapy. Positive surgical margin is one of the most important factors negatively affecting disease-specific, recurrence-free and overall survival rates.
