Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

1.2K
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
1.2K
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

1.6K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.6K
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

1.4K
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
1.4K
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

988
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
988
Esophagus01:24

Esophagus

4.9K
The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
4.9K
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

2.2K
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neutrophil CD64, CD66b, and Serum Thioredoxin as Early Biomarkers of Delayed Fracture-Related Infection After Internal Fixation: A Prospective Cohort Study.

Cureus·2026
Same author

Heavy metal burden and metallothionein-2A expression in relation to severity and short-term outcome in primary osteosarcoma: A longitudinal cohort study.

Journal of clinical orthopaedics and trauma·2026
Same author

Impact of Sex on Viral Shedding and Symptom Severity During Acute COVID-19.

Pathogens & immunity·2026
Same author

Game-day temperatures are predictive of National Football League game outcomes when teams from different climates compete against each other.

Temperature (Austin, Tex.)·2026
Same author

Viral shedding and symptom severity across populations during acute COVID in the ACTIV-2 study.

medRxiv : the preprint server for health sciences·2026
Same author

Therapeutic CD8<sup>+</sup> T cell tissue retention and immunomodulation during ART interruption fail to prevent SIV rebound.

Proceedings of the National Academy of Sciences of the United States of America·2025

Related Experiment Video

Updated: Apr 12, 2026

Robotic Enucleation of Esophageal Leiomyoma
04:19

Robotic Enucleation of Esophageal Leiomyoma

Published on: February 20, 2026

441

Benign esophageal tumors.

Cindy Ha1, James Regan1, Ibrahim Bulent Cetindag1

  • 1Department of Surgery, Division of General Surgery at SIU, Southern Illinois University School of Medicine, 701 North First Street, Springfield, IL 62794, USA.

The Surgical Clinics of North America
|May 13, 2015
PubMed
Summary
This summary is machine-generated.

Benign esophageal and paraesophageal masses and cysts are rare but significant conditions. Diagnosis and management increasingly utilize advanced imaging and minimally invasive surgical techniques for symptomatic or uncertain cases.

Keywords:
Gastrointestinal stromal tumorLeiomyomaMediastinal cyst

More Related Videos

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
10:43

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Published on: December 23, 2022

4.2K
Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes
03:58

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes

Published on: August 2, 2024

2.7K

Related Experiment Videos

Last Updated: Apr 12, 2026

Robotic Enucleation of Esophageal Leiomyoma
04:19

Robotic Enucleation of Esophageal Leiomyoma

Published on: February 20, 2026

441
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
10:43

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Published on: December 23, 2022

4.2K
Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes
03:58

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes

Published on: August 2, 2024

2.7K

Area of Science:

  • Gastroenterology and Surgical Pathology

Background:

  • Benign esophageal and paraesophageal masses and cysts represent uncommon but clinically relevant pathologies.
  • These lesions, while frequently asymptomatic, can manifest diverse symptoms and exhibit variable biological behavior.

Purpose of the Study:

  • To review the contemporary approaches to the categorization and management of benign esophageal and paraesophageal masses and cysts.
  • To highlight the role of advanced diagnostic modalities and minimally invasive surgical techniques.

Main Methods:

  • Review of current literature and diagnostic standards for esophageal and paraesophageal lesions.
  • Emphasis on the utility of endoscopic ultrasound (EUS) and other imaging modalities.
  • Discussion of immunohistochemical analysis when indicated.
  • Overview of minimally invasive surgical approaches: endoscopic, laparoscopic, and thoracoscopic methods.

Main Results:

  • Accurate categorization of these lesions relies on a combination of imaging, including EUS, and sometimes immunohistochemistry.
  • Minimally invasive surgical techniques are becoming the preferred approach for managing symptomatic or indeterminate lesions.

Conclusions:

  • Benign esophageal and paraesophageal masses and cysts require careful evaluation due to their potential for varied clinical presentation and behavior.
  • Modern diagnostic tools and minimally invasive surgical options offer effective management strategies for these rare conditions.