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Serial Enrichment of Spermatogonial Stem and Progenitor Cells SSCs in Culture for Derivation of Long-term Adult Mouse SSC Lines
Published on: February 25, 2013
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In vitro differentiation of sperm from male germline stem cell
P Zheng1, X W Zhao1, X M Zheng1
1College of Animal Science and Technology, Northeast Agricultural University, Harbin, China.
Genetics and Molecular Research : GMR
|May 13, 2015
Abstract:
In this study, we developed a model of sperm in vitro differentiation to study the mechanism of spermatogenesis. We isolated newborn male germ cells for in vitro differentiation. We found that after 4-5 weeks of culture, sperm-like cells were occasionally observed in cell co-culture and the feed-layer. After 1-2 weeks of culture followed by 4-5 weeks of co-culture, sperm-like cells were observed.
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