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Updated: Apr 12, 2026

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
[Marked effect of ECT in the treatment of mania]
Mikael Groth Riis1, Poul Bror Videbech
1Geriatrisk Afdeling G, Aarhus Universitetshospital. mikael.riis@dadlnet.dk.
Abstract:
Mania in bipolar affective disorder can be a serious condition which is usually treated with antipsychotics and mood stabilizers. A systematic search was carried out to review the literature concerning the efficacy of electroconvulsive therapy (ECT) in the treatment of mania. All available studies showed a marked effect of ECT with response/remission rates between 56 and 100%. The randomized controlled trials which compared ECT to pharmacotherapy found that ECT was superior to treatment with psychotropic drugs.
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