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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

Survival in patients with heart failure and normal basal systolic wall motion

E L Kinney1, R J Wright

  • 1Reed Institute, Miami, Florida.

Angiology
|December 1, 1989
PubMed

Insights

Congestive heart failure (CHF) with preserved systolic function is common and linked to better survival. However, distinguishing this condition requires echocardiography, not just bedside assessment.

Area of Science:

  • Cardiology
  • Heart Failure Research

Background:

  • Congestive heart failure (CHF) is a significant clinical challenge.
  • The prognostic impact of preserved systolic function in CHF requires further elucidation.

Purpose of the Study:

  • To evaluate the prognostic significance of preserved systolic function in patients diagnosed with congestive heart failure.
  • To determine if preserved systolic function in CHF is associated with improved patient survival.

Main Methods:

  • Analysis of survival curves in 91 adult patients with congestive heart failure.
  • Patients were stratified into two groups based on fractional shortening: normal (>0.17) versus decreased (≤0.17).
  • Comparison of historical and physical findings between the two groups to ensure baseline similarity.

Main Results:

  • Median survival was 11 months for patients with decreased fractional shortening and 26 months for those with normal fractional shortening.
  • Patients with decreased fractional shortening exhibited significantly shorter survival (p = 0.01).
  • Congestive heart failure with preserved systolic function was found to be common.

Conclusions:

  • Preserved systolic function in congestive heart failure is associated with a better prognosis.
  • Distinguishing CHF with preserved systolic function at the bedside is unreliable; diagnostic tests like echocardiography are necessary.
  • This subgroup may necessitate non-standard therapeutic approaches.

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