Postoperative hemicrania continua-like headache - a case series

Andreas R Gantenbein1, Hakan Sarikaya, Franz Riederer

  • 1Neurorehabilitation, RehaClinic Bad Zurzach, Bad Zurzach, Switzerland, a.gantenbein@rehaclinic.ch.

Insights

Hemicrania continua (HC) can develop after brain surgery. This rare headache disorder, characterized by one-sided head pain and autonomic symptoms, responded to indomethacin treatment in three post-surgical patients.

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Hemicrania continua (HC) is a rare, chronic headache disorder.
  • It is characterized by continuous unilateral head pain, cranial autonomic symptoms, and responsiveness to indomethacin.
  • The underlying pathophysiology of HC remains largely unknown.

Observation:

  • Three patients developed hemicrania continua following cranial surgery.
  • These cases presented with a consistent phenotype of hemicranial headache.
  • Two out of three patients also experienced exacerbations of cranial autonomic symptoms.

Findings:

  • Post-craniotomy onset of hemicrania continua is reported in three cases.
  • All patients exhibited continuous hemicranial headaches.
  • Cranial autonomic symptoms and indomethacin responsiveness were observed.

Implications:

  • The findings suggest that cranial surgery may trigger or activate hemicrania continua.
  • This supports the hypothesis that primary headache disorders can be initiated by surgical insults.
  • Further research into the neurobiological mechanisms linking craniotomy to HC is warranted.
Abstract

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