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Published on: June 21, 2021
A simple fluorescent off-on probe for the discrimination of cysteine from glutathione
Xinghui Gao1, Xiaohua Li, Lihong Li
1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. mahm@iccas.ac.cn lixh@iccas.ac.cn.
Abstract:
A simple and stable fluorescent off-on probe for discrimination of cysteine (Cys) from glutathione (GSH) has been developed by combining resorufin with 7-nitrobenzofurazan. The probe, displaying distinct emission patterns for Cys and GSH at just one excitation wavelength, can be used for simultaneous determination of Cys and GSH in human plasma.

