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Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature
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Amniotic fluid LPCAT1 mRNA correlates with the lamellar body count
Journal of Perinatal Medicine
|May 14, 2015
Abstract:
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is required in the biosynthesis of pulmonary surfactant. This short communication describes our assessment of LPCAT1 mRNA levels in human amniotic fluid. We found a direct correlation between LPCAT1 mRNA copies and the amniotic fluid lamellar body count (LBC). This finding corroborates an association between LPCAT1 and surfactant phospholipid biosynthesis in humans. It may provide a model for future research in perinatal medicine.

