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Related Experiment Videos

Sweating patterns in atopic dermatitis patients.

R M Greene1, R K Winkelmann, T L Opfer-Gehrking

  • 1Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905.

Archives of Dermatological Research
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

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Nine out of ten patients with atopic dermatitis exhibited abnormal sweating patterns. This quantitative sudomotor axon reflex test suggests a link between impaired sweat function and atopic dermatitis.

Area of Science:

  • Dermatology
  • Neuroscience
  • Physiology

Background:

  • Atopic dermatitis is a common inflammatory skin condition.
  • Sweat dysfunction has been anecdotally linked to atopic dermatitis.
  • Quantitative sudomotor axon reflex testing (QSART) is a validated method to assess sweat output.

Purpose of the Study:

  • To quantitatively assess postganglionic sweat output in patients with atopic dermatitis.
  • To investigate the relationship between sweat patterns and atopic dermatitis severity.
  • To determine if abnormal sweating is a characteristic feature of atopic dermatitis.

Main Methods:

  • Ten patients with atopic dermatitis underwent quantitative sudomotor axon reflex testing (QSART).
  • Acetylcholine iontophoresis was used to stimulate axon reflexes.

Related Experiment Videos

  • Measurements included latency, sweat volume, and dynamic sweat pattern from normal skin sites.

    • Main Results:

    • Nine of ten atopic dermatitis patients displayed abnormal sweating patterns or values.
    • Seven patients had significantly abnormal sweat output values.
    • Abnormalities were observed in sweat latency, volume, and dynamic patterns.

    Conclusions:

    • Patients with atopic dermatitis frequently exhibit abnormal sudomotor function.
    • Impaired sweating may be an intrinsic factor contributing to atopic dermatitis.
    • Abnormal sweat patterns could play a role in the pathophysiology of atopic dermatitis.