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Microfluidic flowmeter based on micro "hot-wire" sandwiched Fabry-Perot interferometer.

Ying Li, Guofeng Yan, Liang Zhang

    Optics Express
    |May 14, 2015
    PubMed
    Summary

    We developed a compact microfluidic flowmeter using a Fabry-Perot interferometer (FPI) acting as a hot-wire sensor. This device accurately measures liquid flow rates on a chip, showing promise for biochemical sensing systems.

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    Area of Science:

    • Optics and Photonics
    • Microfluidics
    • Sensor Technology

    Background:

    • Microfluidic systems require precise flow rate measurement for applications in biochemical analysis and diagnostics.
    • Existing flowmeters can be bulky or lack the sensitivity needed for microscale applications.
    • Fabry-Perot interferometers (FPIs) offer high sensitivity and compact form factors suitable for integration.

    Purpose of the Study:

    • To develop and demonstrate a compact microfluidic flowmeter based on a novel FPI sensor.
    • To investigate the performance characteristics of the flowmeter, including sensitivity, dynamic range, and response time.
    • To explore the potential of this FPI-based flowmeter for microfluidic biochemical sensing systems.

    Main Methods:

    • Fabrication of a microfluidic chip integrating a custom-made FPI sensor.

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  • The FPI sensor comprised fiber Bragg grating reflectors and a Co(2+)-doped optical fiber cavity acting as a thermal sensor.
  • Experimental characterization using a tunable pump laser (1480 nm) and varying liquid flow rates.

    • Main Results:

    • Achieved a flow rate sensitivity of 70 pm/(μL/s).
    • Demonstrated a dynamic range up to 1.1 μL/s with a response time in the order of seconds.
    • Obtained a spatial resolution of approximately 200 μm.
    • Investigated the influence of pump power, channel size, and temperature on sensor performance.

    Conclusions:

    • The developed FPI-based microfluidic flowmeter is a compact and sensitive device for liquid flow rate measurement.
    • Its performance characteristics make it a promising component for advanced microfluidic biochemical sensing applications.
    • Further optimization through simulation of the thermal 'hot-wire' cavity can enhance FPI structure design.