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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[Current epidemiology of tuberculosis in Germany]
B Brodhun1, D Altmann1, B Hauer1
1Abteilung für Infektionsepidemiologie, Fachgebiet für respiratorisch übertragbare Erkrankungen, Robert Koch-Institut Berlin.
Tuberculosis (TB) case numbers are stagnating in Germany, with over half of cases now occurring in foreign-born individuals. Multidrug-resistant TB (MDR-TB) is rising, and treatment success rates are below WHO targets, necessitating intensified TB control efforts.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Tuberculosis (TB) remains a significant global infectious disease, posing a relevant public health challenge in Germany.
- Despite global efforts, TB control requires ongoing attention, particularly in industrialized nations.
Purpose of the Study:
- To provide an overview of tuberculosis epidemiology in Germany.
- To emphasize drug resistance patterns and identify predominantly affected population groups.
Main Methods:
- Analysis of surveillance data from the German TB notification system.
- Examination of TB case numbers, drug resistance, patient origin (country of birth, nationality), and treatment outcomes.
Main Results:
- TB case numbers in Germany have stagnated since 2009, reversing a previous decline.
- The proportion of foreign-born patients has exceeded 50%, indicating a demographic shift in TB cases.
- Multidrug-resistant tuberculosis (MDR-TB) increased to 3.4% in 2013, higher than in many comparable European countries, with elevated rates among patients from former Soviet Union countries.
- Treatment success rate was 79%, falling short of the WHO target of 85%.
Conclusions:
- Stagnating TB case numbers and increasing MDR-TB highlight the need for sustained and enhanced tuberculosis control strategies in Germany.
- Focused interventions are crucial for the most affected populations, particularly foreign-born individuals.
- Addressing drug resistance and improving treatment outcomes are key priorities for TB control in Germany.
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