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Related Experiment Video

Updated: Apr 12, 2026

Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein

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Published on: July 29, 2022

Interferon-alpha caused reversible parkinsonism.

Chieh-Sheng Lu¹, Wei-Yau Kao, Jiann-Chyun Lin

¹*Department of Internal Medicine, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan; †Division of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center; ‡Division of Hematology/Oncology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei; §Division of Hematology/Oncology, Department of Internal Medicine, Buddhist Taipei Tzu Chi Hospital, Taipei; and ∥Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.

Clinical Neuropharmacology

|May 14, 2015

Summary

This summary is machine-generated.

Interferon alpha-2a can cause parkinsonism, a rare side effect. Tc-99m-TRODAT-1 SPECT imaging aids in evaluating this condition in patients undergoing interferon therapy.

Area of Science:

Neuroscience
Oncology
Radiology

Background:

Interferon therapy is used for chronic viral hepatitis and malignancies.
Neuropsychiatric adverse effects, including parkinsonism, are potential side effects of interferon treatment.

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