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Published on: March 8, 2012
Human papillomavirus type 16 sequence variation in concurrent vulvar and penile carcinoma in a married couple
Takashi Mitamura1, Hidemichi Watari, Katsushige Yamashiro
1From the *Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo, Japan; †Division of Pathology, Hokkaido Cancer Center, Shiroishi-ku, Sapporo, Japan; and ‡Department of Gynecology, Hokkaido Cancer Society, Higashi-ku, Sapporo, Japan.
Abstract:
We encountered an elderly married couple with concurrent vulvar and penile carcinoma with an Asian variant of human papillomavirus type 16. Asian variants might have an elevated risk of concurrent external genital carcinomas of a male and a female, and analysis of human papillomavirus variants might be important to understand the mechanism of carcinogenesis.
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