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The coated antiseptic tip (CAT) syringe.

Maryanne Mariyaselvam1, Emily Hodges, James Richardson

  • 1The Critical Care Department, The Queen Elizabeth Hospital NHS Trust , Kings Lynn , UK.

Journal of Medical Engineering & Technology
|May 14, 2015
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Summary

The Coated Antiseptic Tip (CAT) syringe effectively decontaminates medical device connectors, significantly reducing bacterial contamination and preventing catheter-related blood stream infections (CR-BSI). This innovation offers a promising strategy to enhance patient safety in healthcare settings.

Keywords:
Catheter-related blood stream infection (CR-SBI)chlorhexidineneedleless connectorssyringesthree way connectors

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Area of Science:

  • Infection Control
  • Microbiology
  • Medical Device Technology

Background:

  • Catheter-related blood stream infections (CR-BSI) represent a significant portion of healthcare-acquired infections (HAI).
  • Colonization of catheter connector hubs and use of contaminated syringes are primary risk factors for CR-BSI.
  • The development of effective decontamination strategies for catheter access points is crucial for infection prevention.

Purpose of the Study:

  • To evaluate the efficacy of the Coated Antiseptic Tip (CAT) syringe in decontaminating common critical care pathogens from needleless valves and three-way connectors.
  • To assess the reduction in bacterial colonization within connector hubs following the use of CAT syringes compared to standard syringes.
  • To determine the potential of the CAT syringe in mitigating the risk of CR-BSI.

Main Methods:

  • Needleless valves and three-way connectors (n=20 each) were intentionally contaminated with common critical care pathogens.
  • CAT syringes and control (non-coated) syringes were used to inject normal saline into the connector hubs at hourly intervals.
  • Internal surfaces of connector hubs were swabbed at 0, 1, and 4 hours post-intervention, and bacterial growth (colony forming units - CFU) was quantified by a blinded microbiologist.

Main Results:

  • Baseline swabbing confirmed 100% bacterial colonization of connector hubs in both groups.
  • The CAT syringe demonstrated a statistically significant reduction in CFU counts at 0 and 1-hour intervals compared to control syringes (p < 0.05).
  • Complete elimination of bacterial growth in both needleless valves and three-way connectors was observed at the 4-hour interval when using the CAT syringe.

Conclusions:

  • The Coated Antiseptic Tip (CAT) syringe is highly effective in disinfecting both three-way and needleless connectors.
  • The CAT syringe significantly reduces bacterial contamination on connector hubs, offering a promising method to prevent CR-BSI.
  • This technology has the potential to improve patient safety by reducing the incidence of healthcare-associated infections related to central venous catheters.