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Updated: Apr 12, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
Characteristics and outcomes of sequential rhegmatogenous retinal detachments
Background And Objective:
While copious data exist regarding the incidence, treatment, and prognosis of rhegmatogenous retinal detachment (RRD), fewer data exist regarding bilateral RRD.
Patients And Methods:
The authors performed a retrospective review of patients with sequential bilateral rhegmatogenous retinal detachments over a 5-year period from January 1, 2009, through December 31, 2014, that were repaired at a single institution. Data were reviewed for 80 eyes of 40 patients, which is the largest series of sequential RRD reported.
Results:
In patients with sequential RRD, the subsequently affected eyes were more likely to present with better initial visual acuity, shorter duration of symptoms, less macula-off status, and less concurrent proliferative vitreoretinopathy. The subsequent eye had better final visual acuity and was less likely to re-detach. Subsequent eyes tended to progress to RRD despite prophylactic retinopexy.
Conclusion:
The constellation of baseline characteristics in which subsequent eyes presented with better initial visual acuity, shorter duration of symptoms, less macula-detached status, and less concurrent proliferative vitreoretinopathy when compared to the initial eye correspond with the findings that subsequent eyes had more successful anatomical and better visual outcomes.

