Related Experiment Videos
Calcium-binding protein from mouse Ehrlich ascites-tumour cells is homologous to human calcyclin
J Kuźnicki1, A Filipek, P E Hunziker
1Nencki Institute of Experimental Biology, Department of Muscle Biochemistry, Warszawa, Poland.
The Biochemical Journal
|November 1, 1989
Abstract:
A Ca2+-binding protein was purified from mouse Ehrlich ascites-tumour cells. The protein forms monomers and disulphide-linked dimers, which can be separated by reverse-phase h.p.l.c. A partial amino acid sequence analysis demonstrated that the protein has an EF-hand structure. A striking homology was found to rat and human calcyclin (a member of the S-100 protein family), which is possibly involved in cell-cycle regulation.