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Published on: February 14, 2019
Modeling-based determination of physiological parameters of systemic VOCs by breath gas analysis: a pilot study
Karl Unterkofler1, Julian King, Pawel Mochalski
1Breath Research Institute, University of Innsbruck, Rathausplatz 4, A-6850 Dornbirn, Austria. University of Applied Sciences Vorarlberg, Hochschulstr. 1, A-6850 Dornbirn, Austria.
None:
In this paper we develop a simple two compartment model which extends the Farhi equation to the case when the inhaled concentration of a volatile organic compound (VOC) is not zero. The model connects the exhaled breath concentration of systemic VOCs with physiological parameters such as endogenous production rates and metabolic rates. Its validity is tested with data obtained for isoprene and inhaled deuterated isoprene-D5.
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