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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
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Pediatric Staphylococcus aureus Infections: Impact of Methicillin Resistance at a Canadian Center

Sergio Fanella1, Joanne Embree1

  • 1From the Section of Pediatric Infectious Diseases, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.

Southern Medical Journal
|May 15, 2015
PubMed
Abstract

Insights

Methicillin-resistant Staphylococcus aureus (MRSA) is a growing concern in pediatric infections. This study highlights MRSA

Area of Science:

  • Pediatric Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) presents a significant challenge in pediatric healthcare.
  • Understanding the epidemiology and clinical characteristics of MRSA infections is crucial for effective management.

Purpose of the Study:

  • To describe the evolving trends and clinical features of Staphylococcus aureus infections, with a focus on MRSA, at a Canadian tertiary pediatric center.
  • To compare characteristics of MRSA infections with methicillin-susceptible S. aureus infections.

Main Methods:

  • A two-component study involving a retrospective review of infection control data and a 1-year prospective surveillance of community-onset S. aureus infections.
  • Comparison of patient demographics and infection presentations between MRSA and methicillin-susceptible S. aureus cases.

Main Results:

  • A steady increase in MRSA infections was observed over time.
  • MRSA was identified in 41% of S. aureus infections during the prospective period.
  • Patients with MRSA were younger (4.9 years) than those with methicillin-susceptible S. aureus (7.7 years).
  • Soft tissue infections were the most common presentation, often associated with inappropriate antimicrobial use.

Conclusions:

  • MRSA accounts for a substantial proportion of S. aureus infections in Canadian pediatric tertiary care settings.
  • Opportunities exist for developing antimicrobial stewardship protocols, particularly for outpatient soft tissue infections.

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