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Invasive Gastric Mucormycosis-a Case Report
Rugved V Kulkarni1, Sanjiv S Thakur1
1Department of General Surgery, Byramjee Jeejeebhoy Medical College, Pune, 411001 Maharashtra India.
The Indian Journal of Surgery
|May 15, 2015
Summary
This case report details a rare instance of invasive gastric mucormycosis, a serious fungal infection, in a diabetic patient with alcoholism. Despite surgical intervention, the patient succumbed to rapid fungal sepsis.
Area of Science:
- Mycology
- Gastroenterology
- Infectious Diseases
Background:
- Mucormycosis is a life-threatening fungal infection, primarily affecting immunocompromised individuals.
- Gastrointestinal mucormycosis is rare, with the stomach being the most frequently involved organ.
- Risk factors include uncontrolled diabetes and chronic alcoholism.
Purpose of the Study:
- To report a rare case of invasive gastric mucormycosis.
- To highlight the challenges in diagnosing and managing this condition.
- To emphasize the association with diabetes and alcoholism.
Main Methods:
- Case report of a 50-year-old male with abdominal pain and fever.
- Clinical presentation included hemodynamic instability and perforative peritonitis.
- Surgical exploration revealed a perforated gastric ulcer; histopathology confirmed invasive mucormycosis via PAS and GMS stains.
Main Results:
- A solitary, large perforated gastric ulcer was identified.
- Histopathology confirmed the presence of fungal hyphae consistent with mucormycosis.
- The patient experienced rapid progression to fungal septicemia.
Conclusions:
- Invasive gastric mucormycosis is an uncommon but severe condition.
- Uncontrolled diabetes and alcoholism are significant risk factors.
- Delayed presentation and rapid progression contribute to high mortality despite treatment.
