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Updated: Apr 12, 2026

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Rare case of gastrointestinal stromal tumor presenting with scrotal metastasis
Richard Thomas1, Smrita Swamy1
1Department of Radiology, St. John's Medical College Hospital, Sarjapur Road, Bangalore, Karnataka 560034 India.
Abstract:
While gastrointestinal stromal tumors frequently metastasize, the scrotum is an extremely rare site of involvement. This case is of a 48-year-old male who, having undergone debulking surgery for metastatic gastrointestinal stromal tumor (GIST) of the small intestine 2 years ago, presented with bilateral scrotal swelling. Ultrasound showed hypoechoic mass lesions surrounding the testis and epididymis bilaterally with extension into the spermatic cord and biopsy established a diagnosis of metastatic GIST of the scrotum. As the processus vaginalis is an extension of the peritoneal cavity, we postulate that it may serve a route of spread in malignancies that involve the peritoneal cavity, as in this case.

