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Updated: Apr 12, 2026
06:38
A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
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Renal cell carcinoma presenting with malignant ascites
Erica Jennison1, Gayathri W Wathuge1, David A Gorard1
1Departments of Gastroenterology and Histopathology, Stoke Mandeville Hospital, Aylesbury, Buckinghamshire HP21 8AL, UK.
JRSM Open
|May 15, 2015
Summary
This report details a rare case of renal cell carcinoma presenting with malignant ascites. The study describes the patient's positive response to sunitinib treatment for this uncommon presentation.
Area of Science:
- Oncology
- Nephrology
Background:
- Renal cell carcinoma (RCC) rarely involves the peritoneum.
- Malignant ascites as a presenting feature of RCC is highly uncommon.
Observation:
- A case of renal cell carcinoma presenting with malignant ascites is described.
- The patient's condition was unusual due to the peritoneal involvement and ascites as the initial symptom.
Findings:
- The patient with renal cell carcinoma and malignant ascites showed a positive response to sunitinib therapy.
- Sunitinib demonstrated efficacy in managing this rare presentation of advanced renal cell carcinoma.
Implications:
- This case highlights the importance of considering RCC in patients with unexplained malignant ascites.
- Targeted therapy with sunitinib may be a viable treatment option for rare cases of RCC with peritoneal metastasis and ascites.
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