Related Experiment Video
Updated: Apr 12, 2026

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
Effects of Resistance Training on Obese Adolescents
Ingrid Dias1, Paulo Farinatti, MariaDas Graças Coelho De Souza
11Laboratory for Clinical and Experimental Research on Vascular Biology, Biomedical Center, Rio de Janeiro State University, Rio de Janeiro, BRAZIL; 2Laboratory of Physical Activity and Health Promotion, Rio de Janeiro State University, Rio de Janeiro, BRAZIL; 3Physical Activity Sciences Graduate Program, Salgado de Oliveira University, Niterói, Rio de Janeiro, BRAZIL; and 4Obesity Unit, Policlínica Piquet Carneiro, Department of Internal Medicine, Faculty of Medical Sciences, Rio de Janeiro State University, Rio de Janeiro, BRAZIL.
Purpose:
The effects of resistance training (RT) alone upon endothelial function, metabolic and hemodynamic profiles, physical fitness, body composition, and inflammatory biomarkers in nondiabetic obese adolescents were investigated.
Methods:
Adolescents were assigned into nonobese control (CG, n = 20; 14.7 ± 1.4 yr) and obese (OB, n = 24; 14.1 ± 1.0 yr) groups. Muscle and skin endothelial reactivity, body composition, at-office and 24-h ambulatory blood pressure, metabolic profile, adipocytokines, aerobic and strength fitness were assessed before and after 12 wk of RT (CG, only at admission).
Results:
After RT, body mass did not change in OB, but significant reductions in body fat (1.6%; P = 0.01), waist circumference (2.9%; P < 0.001), waist-to-hip ratio (3.3%; P < 0.001), homeostasis model assessment for insulin resistance (15.4%; P = 0.02), endothelin-1 (14.2%; P = 0.04), and fibrinogen (6.9%; P = 0.03) were found. Both at-office and ambulatory blood pressure decreased, whereas skin endothelium-dependent vasodilation (32%; P = 0.02), VO2 (14.3%; P = 0.04), and HR (5.3%; P = 0.04) during submaximal exercise and isokinetic strength (extension, 21.3%; flexion, 29.9%; P < 0.0001) increased. Forearm vascular conductance increased at rest (28.1%; P = 0.03) and during postocclusive reactive hyperemia (25.2%; P = 0.02). After RT differences between CG and OB at admission were no longer detected for most outcomes.
Conclusions:
RT alone improved endothelial function, hemodynamic and metabolic profiles, body composition, and physical fitness in nondiabetic obese adolescents regardless of changes in body mass.
More Related Videos
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
06:28A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
Published on: April 28, 2023
Related Concept Videos
Obesity
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion