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Updated: Apr 12, 2026

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
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Reducing falls and improving mobility in multiple sclerosis.

Jacob J Sosnoff1, JongHun Sung

  • 1Motor Control Research Laboratory, Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 906 South Goodwin Ave., Urbana, IL 61801, USA.

Expert Review of Neurotherapeutics
|May 15, 2015
PubMed
Summary
This summary is machine-generated.

Falls are common in people with multiple sclerosis (MS), but fall prevention interventions show promise. Most studies reviewed reported fewer falls and better balance, though more research is needed.

Keywords:
balanceclinical trialsexercisefalls preventionlocomotionmobilityrehabilitationwalking

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Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Public Health

Background:

  • Falls are a significant issue for individuals with multiple sclerosis (MS), leading to injuries and reduced quality of life.
  • Mobility impairments are a primary risk factor for falls in the MS population.
  • While rehabilitation can improve MS mobility, fall prevention strategies require further investigation.

Purpose of the Study:

  • To systematically review existing fall prevention interventions for individuals with MS.
  • To identify the effectiveness of these interventions in reducing falls and improving balance.
  • To highlight gaps in knowledge and recommend future research directions.

Main Methods:

  • A systematic literature search identified ten fall prevention interventions.
  • The review included studies with a total of 524 participants across a range of MS disability levels.
  • Data on fall rates, proportion of fallers, and balance improvements were analyzed.

Main Results:

  • Nine out of ten reviewed interventions reported a reduction in falls or the proportion of fallers.
  • Most interventions showed concurrent improvements in balance alongside reduced fall rates.
  • The majority of participants experienced positive outcomes regarding fall reduction and balance.

Conclusions:

  • Current fall prevention interventions show potential for reducing falls and improving balance in people with MS.
  • Methodological limitations in existing studies prevent definitive conclusions.
  • Further well-designed randomized controlled trials focusing on mobility and fall prevention in MS are essential.