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Related Experiment Video

Updated: Apr 12, 2026

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity
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Studying microbiology with Glenn F. Webb.

Martin J Blaser1

  • 1Human Microbiome Program, Division of Translational Medicine, Department of Medicine, Department of Microbiology, New York University Langone Medical Center, New York, NY 10016, United States.

Mathematical Biosciences and Engineering : MBE
|May 15, 2015
PubMed
Summary

This narrative reflects on the unique conceptualization of Infectious Diseases as a conflict between humans and microbes, distinct from organ-specific medical disciplines. It highlights the interdisciplinary nature of combating microbial threats.

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Area of Science:

  • Medical Microbiology
  • Internal Medicine
  • History of Medicine

Background:

  • The author initiated collaboration with Glenn F. Webb in 1997 while at Vanderbilt University's School of Medicine.
  • The Division of Infectious Diseases operates under a unique paradigm within Internal Medicine.

Discussion:

  • Unlike other Internal Medicine divisions focused on specific organs (e.g., cardiology, pulmonology), Infectious Diseases is conceptualized as a battleground.
  • This perspective frames the study of diseases caused by microorganisms as a conflict between human hosts and microbial pathogens.

Key Insights:

  • Infectious Diseases is defined by its focus on the host-pathogen interaction, a unique approach within medical disciplines.
  • The conceptual framework emphasizes the dynamic interplay and 'war' between humans and microbes.

Outlook:

  • Understanding this conceptual distinction is crucial for advancing research and treatment strategies in infectious diseases.
  • Future research may further explore the evolutionary and ecological aspects of the human-microbe relationship.