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Related Experiment Videos

A simple and compact total artificial heart for temporary use.

L Fujimoto1, J F Chen, W A Smith

  • 1Department of Artificial Organs, Cleveland Clinic Foundation, Ohio 44195-5132.

ASAIO Transactions
|July 1, 1989
PubMed
Summary
This summary is machine-generated.

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A new, low-pressure total artificial heart (TAH) was designed for temporary circulatory support. Its integrated, flat pump design offers better anatomic fit and flow, addressing key challenges in artificial heart development.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Medical Technology

Background:

  • Thromboembolism and poor anatomic fit are significant challenges in total artificial heart (TAH) design.
  • Existing TAH designs often present issues with optimal patient integration and blood flow dynamics.

Purpose of the Study:

  • To develop a novel, pneumatically driven total artificial heart (TAH) for temporary circulatory support.
  • To address limitations of current TAHs by improving anatomic fit, ease of implantation, and blood flow patterns.

Main Methods:

  • A compact, 70 mm3 displacement pusher plate TAH was designed using two integrated flat pumps.
  • The device features a unique pusher plate guide mechanism for linear diaphragm motion and uniform flow.
  • Positioned within the pericardial sac, it mimics natural ventricle placement for improved anatomical integration.

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Main Results:

  • The integrated single-package design minimizes dead space and overall device volume.
  • The pusher plate guide mechanism ensures controlled diaphragm movement, leading to uniform blood flow distribution.
  • A displacement transducer allows for reliable output monitoring and adjustable pumping modes.

Conclusions:

  • The developed TAH offers a practical and efficient solution for temporary circulatory support.
  • The design innovations aim to overcome major hurdles in TAH development, including thromboembolism and anatomic fit.
  • This device shows promise as a suitable temporary heart replacement option.