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Related Experiment Videos

A biolized implantable ventricular assist device compatible with IABP console.

J F Chen1, L K Fujimoto, R R Kiraly

  • 1Department of Artificial Organs, Cleveland Clinic Foundation, OH 44195-5132.

ASAIO Transactions
|July 1, 1989
PubMed
Summary
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A novel pusher plate blood pump offers temporary cardiac support, driven by standard consoles. This reliable, low-cost VAD requires no anticoagulation, showing promise for clinical use.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Medical Technology

Background:

  • Temporary mechanical circulatory support is crucial for managing heart failure.
  • Existing ventricular assist devices (VADs) can be complex and costly.
  • A need exists for simpler, more accessible VADs compatible with standard medical equipment.

Purpose of the Study:

  • To develop and evaluate a low-pressure pneumatic pusher plate blood pump for temporary biventricular assist.
  • To assess the pump's compatibility with standard intraaortic balloon pump (IABP) consoles.
  • To determine the pump's hemocompatibility, performance, and long-term reliability in an animal model.

Main Methods:

  • Development of a disc-shaped, gelatin-coated pneumatic pusher plate pump with a unique guide mechanism.

Related Experiment Videos

  • Testing pump performance in a mock loop, measuring flow rates at varying heart rates.
  • Implantation of the VAD in two calves for extended periods, driven by a Datascope IABP console.

    • Main Results:

    • The pump demonstrated outputs up to 6.7 L/min at 120 bpm in mock loop testing.
    • Calf implants achieved an average output of 5 L/min in both synchronous and fixed-rate modes.
    • No anticoagulation therapy was required during the implantation period, indicating good hemocompatibility.

    Conclusions:

    • The developed pusher plate blood pump is a reliable, cost-effective, and simple VAD.
    • Its compatibility with standard IABP consoles enhances accessibility for clinical use.
    • The device shows significant potential for widespread application in temporary cardiac support.