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Updated: Apr 12, 2026

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Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound
Published on: March 4, 2015
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Retro reproduction: an old imaging technology rewrites the rules of modern embryology
IEEE Pulse
|May 15, 2015
Abstract:
On a video screen, against a black backdrop, 15 spherical blue-green cells vibrate with a quiet energy. Slowly at first, then faster, they begin to roil and roll. Within the confines of their round membrane cases, they divide, becoming two, three, four cells, then those, in turn, divide to become eight. One splits into two, then pauses, struggling to catch up and spinning off pieces of cellular detritus as it does. Near the top, another, by now many cells rich, hollows out and expands, contracts, expands, contracts. It falls in upon itself and then hatches, pouring out from its shell and ballooning to the side.

