Related Experiment Video
Updated: Aug 8, 2026

Measurement of the Pressure-volume Curve in Mouse Lungs
Published on: January 27, 2015
Methods for volume assessment of an air filled compliance chamber
T Izutsu1, R R Navarro, L K Fujimoto
1Department of Artificial Organs, Cleveland Clinic Foundation, OH 44195-5132.
Abstract:
The air-filled (120 ml) compliance chamber employs a Dacron covered Hexsyn-butyl bilaminar diaphragm to minimize gas diffusion. Finite permeability dictates the need for a means to detect the remaining air volume and a refill port for gas addition. X-ray studies were used to detect radiopaque chamber markers in cadavers. Tangential X-ray cinematography enabled detection of chamber volumes less than 100 ml and diaphragm center deflection predicted volume to within +/- 6 ml of the actual volume. An electrically driven left ventricular assist pump (90 cc) was used to evaluate motor current (MC) and intracompliance pressure (IP) as indicators of low compliance volume. Peak MC was a function of both hemodynamic output power and compliance volume. Thus, if the peak current for a given hemodynamic output is known, variances may be indicative of low compliance volumes. The cyclic minimum IP vs. volume was +1, -3, and -13 mmHg for compliance volumes of 120, 90, and 80 cc, respectively. Ejection velocity did not significantly affect IP. In conclusion, X-ray studies and MC are useful as noninvasive means of assessing the need for compliance refill. IP, though measured invasively, is the most sensitive volume-dependent parameter.
More Related Videos
09:03Assessment of Methane and Nitrous Oxide Fluxes from Paddy Field by Means of Static Closed Chambers Maintaining Plants Within Headspace
Published on: September 6, 2018
08:25Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship
Published on: January 8, 2019
Related Concept Videos
Lung Capacity
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Respiratory Volumes and Capacities
Measurement of Air Content in Concrete
The pressure method,...