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Pattern of childhood cancer in University College Hospital, Ibadan during 1991-2010 and comparison with the previous

T O Babatunde, E E U Akang, G O Ogun

    Paediatrics and International Child Health
    |May 16, 2015
    PubMed

    Insights

    Childhood cancer cases in Ibadan, Nigeria have declined, with retinoblastoma now more common than Burkitt lymphoma. This study analyzed cancer patterns in children under 15 years.

    Area of Science:

    • Pediatric Oncology
    • Epidemiology
    • Cancer Research

    Background:

    • Childhood cancer is a significant global health concern, affecting children under 15.
    • Incidence and mortality rates for pediatric cancers vary worldwide.

    Purpose of the Study:

    • To delineate the epidemiological patterns of childhood cancer in Ibadan, Nigeria.
    • To compare current findings with historical data from Ibadan and international studies.

    Main Methods:

    • Retrospective analysis of histologically/cytologically confirmed pediatric cancer cases (<15 years) diagnosed at University College Hospital, Ibadan (1991-2010).
    • Classification of neoplasms using the International Classification of Childhood Cancer, third edition (ICCC-3).

    Main Results:

    • A total of 625 cases were identified, with lymphomas (22.4%) being the most frequent, followed by retinoblastomas (21%).
    • A notable decrease in the proportion of lymphomas, particularly Burkitt lymphoma, was observed compared to previous periods.
    • Retinoblastoma has emerged as the most common individual childhood cancer in this cohort.

    Conclusions:

    • A decline in childhood cancer cases at the University College Hospital, Ibadan over the past two decades.
    • This decline may be attributed to the development of additional specialized cancer treatment centers in the region.
    • Shifting cancer landscape in Ibadan with retinoblastoma surpassing Burkitt lymphoma in incidence.
    Abstract

    Keywords:
    Childhood cancer,IbadanNigeria,Pattern,

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