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Updated: Apr 12, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
Published on: January 15, 2015
Optogenetics and deep brain stimulation neurotechnologies
Krishnakanth Kondabolu1, Marek Mateusz Kowalski, Erik Andrew Roberts
1Biomedical Engineering Department, Boston University, Boston, MA, USA.
Abstract:
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines light and genetic methods to control or monitor neural activity patterns, has proven to be revolutionary in understanding the functional role of specific neural circuits. We here briefly describe recent advance in optogenetics and compare optogenetics with deep brain stimulation technology that holds the promise for treating many neurological and psychiatric disorders.

