Related Experiment Video
Updated: Apr 12, 2026

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
Published on: September 12, 2020
Baclofen overdose from possible intrinsic malfunction of SynchroMed II pump
Justin R Davanzo1, Elias Rizk1
1Department of Neurosurgery, Penn State Hershey Medical Center, Hershey, Pennsylvania.
Abstract:
This is a case report illustrating an overdose of baclofen in a 10-year-old boy due to a likely malfunction of a SynchroMed II pump. This ultimately necessitated a pump replacement. One-year follow-up showed no further incidents of baclofen overdose, with multiple pump refills.
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