Related Experiment Video
Updated: Apr 12, 2026

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Published on: January 5, 2017
Cutaneous malignancy of the head and neck
Wojciech K Mydlarz1, Randal S Weber1, Michael E Kupferman1
1Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Nonmelanoma skin cancers (NMSCs) are common head and neck cancers. Effective treatments exist, but prevention through sun protection and early detection is key for managing these skin cancers.
Area of Science:
- Dermatology
- Oncology
Background:
- Nonmelanoma skin cancers (NMSCs) are the most prevalent malignancies affecting the head and neck.
- Basal cell carcinoma and squamous cell carcinoma represent the predominant NMSC subtypes.
Purpose of the Study:
- To outline current therapeutic strategies for head and neck NMSCs.
- To emphasize the importance of preventative measures and early detection in managing NMSCs.
Main Methods:
- Review of established treatment modalities for NMSCs.
- Discussion of multidisciplinary team approaches for complex cases.
- Emphasis on primary prevention and screening protocols.
Main Results:
- Surgical interventions like wide local excision, Mohs surgery, and lymphadenectomy, often combined with adjuvant radiation, achieve high cure rates.
- These treatments effectively balance oncological control with functional and cosmetic preservation.
- Multidisciplinary evaluation is crucial for advanced or aggressive NMSC presentations.
Conclusions:
- Head and neck NMSCs are highly treatable with established methods.
- Preventative strategies, including sun avoidance and early lesion evaluation, are paramount.
- A coordinated, multidisciplinary approach optimizes outcomes for NMSC patients.
More Related Videos
06:08Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Published on: June 2, 2023
07:29Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Arteries of the Head and Neck
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.