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Prognosis after surgery for colonic Crohn's disease
H A Andrews1, P Lewis, R N Allan
1Gastroenterology Unit, General Hospital, Birmingham, UK.
The British Journal of Surgery
|November 1, 1989
Summary
This study analyzed 360 Crohn's colitis patients over 14.9 years, finding surgery often necessary but effective. Most patients achieve good health post-treatment, with remission possible at all disease sites.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Inflammatory Bowel Disease Research
Background:
- Crohn's colitis prognosis is complex, involving long-term outcomes like operations, recurrence, and mortality.
- Understanding long-term patient status is crucial for managing this chronic condition.
Purpose of the Study:
- To analyze the long-term prognosis of Crohn's colitis patients based on initial disease site.
- To evaluate operation rates, remission, morbidity, mortality, and current patient status.
Main Methods:
- Retrospective analysis of 360 Crohn's colitis patients.
- Follow-up for a mean of 14.9 years, grouped by primary site of disease.
- Data collection on operation rates, remission, reoperation, mortality, and current health status.
Main Results:
- Overall operation rate was 76%.
- Remission rates varied by disease site (11-38%).
- Cumulative reoperation rates at 10 years ranged from 21% to 60% depending on surgical procedure. Mortality rate has decreased over time, with most patients currently well.
Conclusions:
- Surgical treatment can effectively restore health in Crohn's colitis patients with persistent symptoms.
- While long-term outcomes require management, many patients achieve good current health status.