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Updated: Apr 12, 2026

Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Complications and Risk Assessment of 25 Years in Pediatric Pacing
B Jakub Wilhelm1, Marc Thöne2, Tarik El-Scheich3
1Easton Hospital, Department of Surgery, Drexel University College of Medicine, Easton, Pennsylvania; Division of Cardiovascular Surgery, Heinrich Heine University Hospital Düsseldorf, Düsseldorf, Germany.
Pediatric cardiac pacing presents challenges, with endocardial leads showing higher rates of lead problems and venous thrombosis, especially in younger children. An individualized approach is crucial for both endocardial and epicardial systems.
Area of Science:
- Pediatric Cardiology
- Biomedical Engineering
- Cardiac Electrophysiology
Background:
- Pediatric pacemaker implantation is a specialized field with unique surgical challenges due to small patient anatomy.
- Children undergoing pacemaker procedures face specific complications distinct from adult populations.
- This study investigates complications and risk factors associated with endocardial and epicardial pacemaker systems in pediatric patients.
Purpose of the Study:
- To analyze complications in pediatric patients with endocardial and epicardial pacemaker systems.
- To identify specific risk factors associated with pacemaker implantation in children.
- To compare the outcomes of endocardial versus epicardial pacing in pediatric populations.
Main Methods:
- Retrospective evaluation of pacemaker-related operations in pediatric patients (<18 years) from 1985-2010.
- Collection of demographic data including age, height, and weight.
- Separate analysis of idiopathic and postoperative dysrhythmias.
Main Results:
- 149 operations in 73 pediatric patients were analyzed.
- Epicardial leads had higher pacing thresholds (17.2%) compared to endocardial leads (2.9%).
- Endocardial leads experienced more lead problems (30.4%) and venous thrombosis (13.7%), particularly in patients <15 kg.
Conclusions:
- Pediatric cardiac pacing is complex, often requiring multiple reoperations throughout a patient's life.
- Neither epicardial nor endocardial pacing systems demonstrate clear superiority.
- An individualized treatment strategy is essential for pediatric pacemaker patients.
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