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Hematological findings in children with brucellosis
Adalet Aypak1, Cenk Aypak2, Yasemin Bayram3
1Department of Infectious Diseases and Clinical Microbiology.
Summary
Childhood brucellosis often presents with non-specific hematological changes. Isolated thrombocytopenia is a key finding, suggesting brucellosis in endemic areas.
Area of Science:
- Pediatric infectious diseases
- Hematology
- Microbiology
Background:
- Brucellosis is a zoonotic infection causing diverse hematological abnormalities.
- Understanding these hematological findings in children is crucial for diagnosis.
Purpose of the Study:
- To evaluate the spectrum of hematological findings in pediatric brucellosis.
- To identify key hematological indicators for diagnosing childhood brucellosis.
Main Methods:
- Retrospective analysis of medical records of pediatric brucellosis patients.
- Inclusion criteria: children diagnosed with brucellosis over a one-year period.
- Data collected: patient demographics, hematological parameters, and microbiological results.
Main Results:
- Sixty-nine pediatric patients diagnosed with brucellosis.
- Most common finding: thrombocytopenia (15.9%). Other findings included thrombocytosis, leukopenia, anemia, and bicytopenia.
- Lower platelet counts were observed in patients with positive blood cultures for Brucella spp.
Conclusions:
- Brucellosis should be considered in the differential diagnosis of isolated thrombocytopenia in children from endemic regions.
- Hematological findings, particularly thrombocytopenia, can aid in the early detection of brucellosis in pediatric populations.
