Related Experiment Video
Updated: Oct 4, 2026
In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging
Published on: June 8, 2017
Rhinocerebral mucormycosis: a case report with magnetic resonance imaging findings
G R McDevitt1, M J Brantley, M A Cawthon
1Brooke Army Medical Center, Department of Radiology, Fort Sam Houston, TX 78234-6200.
Abstract:
Mucormycosis is a rare fungal disease most often encountered in patients who are diabetic, immunocompromised, severely burned, or who have a history of intravenous drug abuse. Intracranial presentation includes the isolated cerebral and the more common rhinocerebral forms. The computed tomography picture in mucormycosis is well documented. The magnetic resonance (MR) findings associated with mucormycosis have not been previously described. We report a case of rhinocerebral mucormycosis in a poorly controlled diabetic man where the MR findings of cavernous sinus thrombosis and thrombosis of the cavernous portion of the internal carotid artery demonstrated progression of the patient's disease in spite of his stable clinica course. The results of the MR findings directly altered the patient's therapy, thus leading to a favorable outcome.
Insights
This study highlights the crucial role of Magnetic Resonance (MR) imaging in diagnosing and managing intracranial mucormycosis, a rare fungal infection. Early MR findings aided in timely therapy adjustments, leading to a positive patient outcome.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Radiology
Background:
- Mucormycosis is a rare, aggressive fungal infection.
- Intracranial involvement presents as cerebral or rhinocerebral forms.
- Risk factors include diabetes, immunosuppression, and drug abuse.
Observation:
- Computed tomography (CT) findings are established.
- Magnetic Resonance (MR) imaging findings in mucormycosis were previously undescribed.
- A case of rhinocerebral mucormycosis in a diabetic patient is presented.
Findings:
- MR revealed cavernous sinus thrombosis and internal carotid artery thrombosis.
- Disease progression was noted despite a stable clinical course.
- MR findings directly influenced patient management and therapy.
Implications:
- MR imaging is vital for diagnosing intracranial mucormycosis.
- Early detection of vascular complications via MR is critical.
- Timely therapeutic adjustments based on MR findings improve patient prognosis.
Related Concept Videos
01:24Magnetic Resonance Imaging
01:27Cryptococcal Meningitis