Oncology patients overwhelmingly support tissue banking.

Area of Science:

• Biomedical Research
• Oncology
• Biobanking

Background:

• Translational research requires human tissue for disease etiology and treatment development.
• Biobanks are crucial for research but raise ethical considerations for donors.
• This study quantifies oncology patient preferences for tissue biobanking.

Purpose of the Study:

• To explore oncology patient willingness to donate tissue for biobanking.
• To identify factors influencing donation decisions.
• To understand patient preferences for tissue use, consent, data linkage, and feedback.

Main Methods:

• A quantitative, cross-sectional survey was administered to oncology outpatients.
• Participants completed touchscreen surveys on donation willingness and preferences.
• Validated items explored consent systems, data linkage, and communication.

Main Results:

• 84% of 224 oncology outpatients were willing to donate tissue.
• High willingness for future use (96%) and linkage to medical records (62%).
• Preferred blanket consent (71%) and receiving general research results (79%).

Conclusions:

• Oncology patients show strong willingness to participate in tissue biobanks.
• Findings support exploring 'opt-out' consent models alongside opt-in.
• Tissue banking programs should prioritize clear communication and patient-preferred consent/feedback protocols.