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Multimodality imaging of retinal astrocytoma
Ekaterina Semenova1,2, Chiara Veronese3, Antonio Ciardella3
1The New York Eye Cancer Center, New York, NY - USA.
European Journal of Ophthalmology
|May 19, 2015
Summary
This study characterizes retinal astrocytomas (RA) using multiple imaging techniques. Retinal astrocytomas are typically non-progressive, amelanotic tumors found near the optic disc.
Area of Science:
- Ophthalmology
- Oncology
- Medical Imaging
Background:
- Retinal astrocytomas (RA) are rare intraocular tumors.
- Understanding their imaging characteristics is crucial for diagnosis and management.
Purpose of the Study:
- To cross-characterize retinal astrocytomas (RA) using various ocular diagnostic imaging techniques.
- To define the unique imaging features of RA.
Main Methods:
- Utilized fundus photography, fluorescein angiography, optical coherence tomography (OCT), fundus autofluorescence, and ultrasonography.
- Analyzed imaging data from patients with sporadic and tuberous sclerosis-associated RA.
Main Results:
- RA were typically amelanotic, white to yellow, and often juxtapapillary (63%).
- OCT showed vitreous seeding (75%) and intraretinal fluid (25%).
- Ultrasound revealed a mean thickness of 1.4 mm; no tumor growth was observed over a mean follow-up of 54 months.
Conclusions:
- Retinal astrocytomas are generally non-progressive, amelanotic tumors with characteristic imaging findings.
- A mulberry-shaped surface and moderate to high internal reflectivity on ultrasound are notable features.
- Imaging aids in differentiating RA and monitoring for growth.
