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Related Experiment Video

Updated: Apr 12, 2026

Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults
06:12

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Prism adaptation and spatial neglect: the need for dose-finding studies.

Kelly M Goedert1, Jeffrey Y Zhang2, A M Barrett3

  • 1Department of Psychology, Seton Hall University South Orange, NJ, USA.

Frontiers in Human Neuroscience
|May 19, 2015
PubMed
Summary

Spatial neglect treatment using prism adaptation may require fewer sessions than standard protocols. Preliminary data suggest a reduced dose is effective and maintained long-term, improving accessibility for stroke survivors.

Keywords:
dose-findinginpatient rehabilitationprism adaptationspatial neglect

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Clinical Psychology

Background:

  • Spatial neglect affects 50-70% of right-brain stroke survivors, leading to significant disability and dependence.
  • Current prism adaptation protocols for spatial neglect are intensive and often impractical for rehabilitation settings.
  • Existing research indicates that even one to two sessions of prism adaptation can induce neuroplastic changes.

Purpose of the Study:

  • To investigate the effectiveness of a reduced-dose prism adaptation protocol for spatial neglect.
  • To determine if a shorter treatment period can yield significant and lasting benefits for stroke patients.
  • To inform the development of more accessible and practical treatments for spatial neglect.

Main Methods:

  • Preliminary data analysis from a study involving spatial neglect patients undergoing prism adaptation therapy.
  • Comparison of treatment effects following a reduced number of prism adaptation sessions (four to six) versus standard protocols.
  • Assessment of treatment maintenance at three to four weeks post-intervention.

Main Results:

  • Preliminary findings suggest that four to six sessions of prism adaptation may induce a substantial treatment effect for spatial neglect.
  • The observed treatment benefits were maintained for at least three to four weeks after the intervention period.
  • These results indicate a potential for a lower-dose, more accessible treatment approach.

Conclusions:

  • A reduced-dose prism adaptation protocol shows promise for treating spatial neglect in stroke survivors.
  • Shorter treatment durations could enhance the feasibility and availability of prism adaptation therapy.
  • Further investigation via a randomized clinical trial is warranted to establish the minimal effective dose.