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[Prolonged mydriasis caused by Lamaline].

S Maizoub, E Autret, Y Furet

    Bulletin Des Societes D'Ophtalmologie De France
    |March 1, 1989
    PubMed
    Summary
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    Atropine derivatives in medications can cause prolonged pupil dilation and cycloplegia. Individual ocular sensitivity necessitates caution with even small doses of these drugs.

    Area of Science:

    • Ophthalmology
    • Pharmacology

    Background:

    • Atropine derivatives are common ingredients in various combination medications.
    • Their presence is frequently overlooked in therapeutic contexts.

    Observation:

    • A case report details prolonged bilateral non-reactive mydriasis (pupil dilation) and cycloplegia (paralysis of the ciliary muscle).
    • This reaction was associated with a therapeutic dose of Lameline suppositories.

    Findings:

    • The case suggests a potential for individual susceptibility and specific ocular sensitivity to atropine derivatives.
    • Even therapeutic doses may trigger adverse ocular effects in sensitive individuals.

    Implications:

    • Clinicians should be vigilant about identifying atropine derivatives in all medications.

    Related Experiment Videos

  • Contraindications for atropine derivatives must be respected, regardless of dosage, due to potential individual hypersensitivity.