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Updated: Apr 12, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
Case report: a rare cause of metabolic alkalosis
Silvia M Titan1, Otávio C E Gebara2, Silvia H V Callas2
1Nephrology Division, Hospital das Clínicas, Sao Paulo University Medical School, Sao Paulo, Brazil.
Abstract:
A case of a 66-year-old white man with recent onset of oedema, hypertension, metabolic alkalosis and profound hypokalaemia is described. The initial laboratorial workup showed that urinary chloride concentration and potassium excretion were increased, suggesting a state of hyperaldosteronism. Nonetheless, renin activity was low and aldosterone levels were normal. The metabolic alkalosis seen in this case was due to a rare cause, the ectopic adrenocorticotropic hormone syndrome. A literature review in the subject is presented.
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