Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nucleic acids02:43

Nucleic acids

199.1K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
199.1K
Nucleic Acids02:43

Nucleic Acids

52.4K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
52.4K
Nucleic Acid Structure01:25

Nucleic Acid Structure

10.4K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
10.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Agnostic material classification using differential de Bruijn graphs of DNA imprints.

bioRxiv : the preprint server for biology·2026
Same author

The Origin of Life in the Light of Evolution.

ArXiv·2026
Same author

Overestimating zero-shot fitness prediction: Broad benchmarks mask local failures and practical limitations.

bioRxiv : the preprint server for biology·2026
Same author

Integrating Transcription Factors with Electrochemical Pendulum Bioanalysis for Hormone Detection.

Journal of the American Chemical Society·2026
Same author

Fieldable isothermal nucleic acid test for rapid semi-quantitative visual readout of enterococci in recreational waters.

PeerJ·2026
Same author

Correction: Injectable hydrogel-based localized delivery of IDO-galectin-3 mitigates neuroinflammation and promotes neuronal sparing after spinal cord contusion in rats.

Journal of materials chemistry. B·2026

Related Experiment Video

Updated: Apr 12, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

21.4K

3D Printing with Nucleic Acid Adhesives.

Peter B Allen1, Zin Khaing1, Christine E Schmidt1

  • 1Departmet of Chemistry and Biochemistry, University of Texas at Austin , 1 University Station, Austin, Texas, United States.

ACS Biomaterials Science & Engineering
|May 19, 2015
PubMed
Summary

Researchers developed a shape-retaining colloidal gel using DNA-coated microparticles. This DNA-mediated assembly enables cost-effective, 3D-printable materials for tissue engineering applications.

Keywords:
3D printingDNAcolloidal gelhybridizationmicroparticlesself-assembly

More Related Videos

Simple, Affordable, and Modular Patterning of Cells using DNA
08:59

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

4.8K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.3K

Related Experiment Videos

Last Updated: Apr 12, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

21.4K
Simple, Affordable, and Modular Patterning of Cells using DNA
08:59

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

4.8K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

15.3K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Tissue Engineering

Background:

  • DNA nanotechnology enables precise control over material assembly at the nanoscale.
  • Conventional DNA-mediated assembly is often costly and difficult to scale for macroscopic applications.

Purpose of the Study:

  • To develop a cost-effective, scalable method for creating shape-retaining colloidal gels using DNA-mediated assembly.
  • To demonstrate the potential of this material for 3D printing and hosting living cells for tissue engineering.

Main Methods:

  • Assembly of microparticles into a colloidal gel utilizing specific DNA:DNA interactions as a "smart glue".
  • Extrusion of the colloidal gel using a 3D printer to create centimeter-sized objects.
  • Characterization of the material's shape retention, microscale structure control via DNA binding, and biocompatibility.

Main Results:

  • The colloidal gel demonstrated shape retention after 3D printing extrusion.
  • DNA binding behavior allowed for control over particle connectivity and microscale structure.
  • DNA-coated microparticles significantly reduced assembly costs compared to traditional DNA nanotechnologies.
  • The material was assembled under biofriendly conditions and successfully hosted growing cells.

Conclusions:

  • DNA-mediated assembly of microparticles offers a novel, cost-effective approach for creating macroscopic, shape-retaining colloidal gels.
  • This technology facilitates the engineering of bioprinted tissues by providing a suitable matrix for cell growth and organization.
  • The developed material bridges the gap between nanoscale DNA assembly and macroscale applications in regenerative medicine.